Get 3 feasible methods fromMiniTool.
If you are using Outlook 2010/2013, you might encounter an 0x8004010 error.
The complete error alert is 0x8004010F: Outlook data file cannot be accessed.

It is a common issue notification.
First, locate the default Outlook data file.
Step 1: Press theWindowskey +Rkey at the same time to open theRundialog box.

TypeControl Panelin the box and click theOKbutton.
Step 2: ChooseView by: Small icons.
ClickMailand click theShow Profilesbutton.
Step 3: Select your current Outlook profile and click thePropertiesbutton.
Step 4: ClickData Files.
Next, create new Outlook profile.
Step 1: fire up the Mail Setup window by using the Control Panel again.
Step 3: jot down a name for the new profile and clickOK.
Step 4: Choose thePOP or IMAP(orInternet E-mail) option, and clickNext.
Step 5: key in your email information and then clickNext.
Step 6: ClickFinish.
Finally, configure the new Outlook profile as the default profile.
Step 1: Open Mail with the Control Panel again.
Step 2: ClickShow Profiles, chooseAlways use this profileand then choose the new profile from the drop-down menu.
Step 3: ClickOKto exit Mail.
Now, see if the Outlook error 0x8004010F still persists.
Thus, you could make a run at disable your antivirus utilities to fix this issue.
Step 1: Right-smack the taskbar and choose theTask Manageroption.
Step 2: Switch to theStartuptab, right-click your antivirus software and then choose theDisablebutton.
Thus, you shouldturn off Windows DefenderFirewall.
Step 1: Typecontrol panelin the search bar and clickControl Panelto open it.
Step 2: ChooseView by: Small iconsand then clickWindows Defender Firewallto open it.
Step 3: ClickTurn Windows Defender Firewall on or offfrom the left side.
Step 4: Click bothTurn off Windows Defender FirewallunderPrivate web link settingsandPublic web link settingsto disable Windows Defender Firewall.
Step 5: ClickOKto exit the window.
After you finish the steps above, you could peek if Outlook error 0x8004010F still exists.
Bottom Line
These are all the methods to solve the error 0x8004010F in Windows 10.
Hope this post is helpful for you.