Check out this post to find out how to fix the location not available error.
Error-Location Is Not Available
Have you ever received the warning Location is not available in Windows?
But when I venture to read via “Computer” I get this error.

The location is not available
E:/is not accessible
Access is denied.
Lets discuss the most common situations where you may encounter this error.
Situation 1: Location is not available The volume does not contain a recognized file system.

The volume does not contain a recognizedfile system.
kindly verify that all required file system drivers are loaded and that the volume is not corrupted.
Why does this error happen?

So, users are not allowed to access it.
How to fix this error?
When trying to open a drive, you may get an fault signal saying Location is not available.

F:\ is not accessible Access is denied (F is thedrive letterof the inaccessible hard drive).
Various reasons can cause this error, including mistaken operation, virus invasion, etc.
Situation 4: Location is not available The file or directory is corrupted and unreadable.

As a result, you cannot access data stored on the USB hard drive.
Situation 5: Location is not available Desktop blank and apps deleted.
When I give a shot to pop up my desktop.
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I got an error: “C:\Windows\system32\config\systemprofile\Desktop refers to an unavailable location.
It could be on a hard drive on this computer or a online grid.
If it still cannot be located, the information might have been moved to a different location.

answers.microsoft.com
This error usually occurs after installing acorrupt Windows updateon your box or when the system suddenly crashes.
Consider the following scenario:
You have a Windows 7 computer that supports sleep and hibernate mode.
Additionally, you may receive error messages such as the following:
The location is not available.

Cant Access X:\
The specified internet name is no longer available.
The local gadget name is already in use.
This connection has not been restored.

This issue occurs because theServer Message Block(SMB) session is deleted on the server side.
4 Methods to Fix Location Is Not Available
Method 1.
The steps are shown below:
Step 1: Right-click theWindows keybutton and selectDisk Management.

Step 2: Right-tap the target drive and selectFormat, and then clickOKon the pop-up message box.
Do the files copied to a USB drive disappear?
Read this post to see how to recover disappeared data and fix the USB drive.

Method 2.
Therefore, before fixing The location is not available, you had better transfer its data out.
MiniTool Power Data Recovery is a good choice for lost data recovery.

Now, it’s possible for you to download this software to try it out.
Launch MiniTool Power Data Recovery.
Under theLogical Drivestab, pick the drive which prompts the Location is not available error, and clickScan.
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Step 2: In the process of scanning, you might double-click a desired file to preview it.
Then check all needed files and clickSaveto choose a safe place to store them.
Note:MiniTool Power Data Recovery Free Edition can only recover no more than 1GB of data.
To break this limitation, just choose Personal or the above editions.
In this case, you might have a go at turn on the user full control to resolve it.
Step 2: Under theSecuritysection, chooseEdit.
Step 3: snag the user name that you want to give permission to and checkFull controlbelowAllow.
Step 4: ClickApplyandOKto apply all the changes.
Then power cycle your PC to check whether the issue has been fixed.
The steps are as follows:
Step 1: Right-click theWindows keybutton and chooseTask Manager.
Step 2: Under theProcessessection, right-clickWindows Explorerand chooseRestart.