Some Windows 11/10 users report that they have noticed that keyboard shortcuts are not working in Word.
Why does the issue appear?
How to fix the issue?

Continue to read this post fromMiniTool.
Some Word users encounter the keyboard shortcuts not working in Word issue when using the app.
This issue can be found on Windows 11/10/8/7.

The detailed information is as follows.
Solution 1: Repair Microsoft Office
Microsoft provides an effective built-in quick repair tool to repair Office.
Step 1: TypeControl Panelin theSearchbox.

Step 2: Click theUninstall a programbutton underPrograms.
Step 3: Find and right-hit the Office software to selectChange.
Step 4: ChooseQuick RepairorOnline Repairbased on your situation according to the on-screen instructions.

Here is how to do that:
Step 1: Open Microsoft Word.
Go to File > Options.
Step 2: Click CustomiseRibbon>Customise….
Step 3: ClickReset allto reset all customized keyboard shortcuts.
Solution 3: Boot Word in Safe Mode
Sometimes, add-ons can cause problems.
Step 1: PressWindows+Rto openRun.
Step 2: Go toFile > Options.
Step 3: ClickAdd-insand clickGo….
Step 4: Select any add-ins that appear in the list, and clickRemove.
Step 1: Launch Word, and click theFile>Options.
Step 2: Go to theLanguagetab, and clickAdd a Language….
Step 3: SelectEnglish (United States)from the list, and then click theInstallbutton.
if you bump into the same issue, you could try the methods mentioned above.