It is not stable currently and always brings many bugs & errors.
To know some details, go to this post Will Windows 11 Bring Us Errors?
Here are Some Examples!

Besides, it’s possible for you to encounter another issue automatic sample submission turns off.
This is the topic that we focus on in this post.
To protect your PC, you should probably re-unlock the setting after every boot, which is annoying.

Well then, how can fix this issue in Windows 11?
Get solutions from the following part now.
Step 1: PressWin + Ito open Windows 11 tweaks.

Then, clickWindows Updatefrom the left sidebar.
Alternatively, you could clickWin + Rto get theRundialog, typems-prefs:windowsupdateand clickOKto open Windows Update.
Step 2: ClickCheck for updates.
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If Windows finds some available updates includingKB5004300, it will download and install them.
Step 3: You will be asked to restart the PC to install this update.
This is to keep the functionality of this component of Windows Defender enabled in between restarts.
Here is how to do this task:
Step 2: Go to this path:Computer\HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows Defender.
Step 3: Right-click Windows Defender and chooseNew > Key.
Step 4: Rename the new key toSpyNet.
Name the new key asDisableBlockAtFirstSeen.
Step 6: Double-click it, setBasetoHexadecimaland the value data to0.
Step 7: Also, create a key calledSpynetReportingandSubmitSamplesConsent.
Then, setBasetoHexadecimaland the value data to1for these two keys.
Step 8: reset your PC and see if your issue is solved.
Modify Your Group Policy
Windows 11 Home vs Pro, what are the differences?
Check the answers in this post.
Step 1: PressWin + R, typegpedit.mscand clickOK.
Step 2: Go toComputer Configuration >Administrative Templates >Windows Components > Microsoft Defender Antivirus >MAPS.
Step 3: Go to the right section and findSend file samples when further analysis is required.
Step 4: Double-click it and selectEnabled.
Step 5: Save the change and restart the PC.
These are the ways to fix your issue.