According to statistics, iTunes is used frequently to play audios and videos.
Besides, its the official tool to manage Apple devices, including iPhone, iPad, and iPod Touch.
What causes the error -50 iTunes and how to fix it?

However, its more than just a player.
you’re free to still use it as an internet radio broadcaster or mobile unit management tool.
Connecting iPhone to iTunes on a Windows computer and syncing iPhone with iTunes are ordinary user actions.
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iTunes Could Not Connect To This iPhone: Error 0xE8000065!
An Unknown Error Occurred: iTunes error -50
What is iTunes error?
It refers to the error that occurred in your iTunes app while using it.
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You may run into a series of errors in iTunes, just like any other problems and apps.
Now, lets get to know more about the possible causes and useful solutions to this error code iTunes.
How To Fix Error 14 On iTunes When Updating iOS.

hey fix the connection failure or slow connection problem.
After that, make a run at remove your iPhone and then reconnect it again to iTunes.
Besides, you might make a run at fix the error by restarting your iPhone.

just go to check whether your firewall or antivirus program is blocking the iTunes program or not.
