It is not hard to fix.
it’s possible for you to refer to this post offered byMiniTool Solutionto get some useful methods.
When you attempt to send Outgoing emails with various versions of Outlook, you may encounter the error 0x80042109.

If you continue to receive this message, contact your server administrator or Internet service provider (ISP).
Whats causing the Outlook warning pop-up 0x80042109?
Here are some possible reasons: Incorrect SMTP prefs, 3rd party firewall interference or add-in interference.

Now, follow the instructions below to fix this 0x80042109 error.
If you find that Outlook couldnt complete your search and you want to fix it, read this post.
you might get some useful solutions from this post.

Heres a quick step-by-step guide on how to do that.
Step 1: Completely close Outlook and all associated instances.
Step 2: TypeControl Panelin theSearchbar, navigate to it and click to open it.
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Step 3: SetView by: Small icons.
FindMailand click to open theMail Setup Outlookwindow.
Step 4: Click theE-mail Accounts…button.
Step 6: Click theMore prefs…button in the bottom-right corner to open theInternet E-mail Settingswindow.
Step 7: Go to theOutgoing Servertab and checkMy outgoing server (SMTP) requires authentication.
Step 8: Switch to theConnectiontab and checkConnect using my local area data pipe (LAN).
Step 9: Then, go to theConnectiontab.
In this case, you might have a go at kill the third-party firewall triggering this false positive.
Comodo and McAfee are the most common suites that cause this jot down of behavior.
However, this operation is not enough for most firewall suites.
Even if the real-time security protection is disabled, the same security rules will remain.
In this case, you should whitelist the communication between Outlook and the email server.
Here is a quick guide on how to do that.
Depending on the security tool you use, the steps to perform this action will vary.
Uninstall the Third-Party Security Suite
Step 1: PressWinkey +Rkey, typeappwiz.cpland pressEnterto open thePrograms and Featuresmenu.
Step 2: Next, find the firewall that you want to uninstall through the list of installed applications.
Step 3: Select it and chooseUninstall.
Then, follow the instructions to complete the uninstallation.
Step 4: After the uninstallation is complete, cycle your box.
Step 2: pick the provided link to download the removal tool and then launch it.
Now, repeat the previous operation that triggered the 0x80042109 error to see if the problem is resolved.
Safe Mode will launch the system without any other third-party modules.
Here are the steps toopen Outlook in Safe Modeand find the add-in that is causing issues.
Step 2: PressWinkey +Rkey, typeOutlook.exe /safeand pressEnterto open Outlook in Safe Mode.
Step 3: If you have multiple profiles, confirm your Outlook profile that you want to use.
Step 4: Go to theFiletab and clickOptions.
Step 5: Click theAdd-instab from the left side.
Then move over to the right side, selectCOM Add-insfrom theManagemenu and clickGoto launch the menu.
Step 6: To disable every installed Add-in, uncheck the boxes associated with it and then clickOK.
Once you disable every add-in, restart Outlook and see if the 0x80042109 error is fixed.
If yes, proceed to systematically re-turn on the add-ins previously disabled until you find the culprits.
If you are encountering the 0x800ccc0f Outlook error, you are in the right place.
This post will show you some possible solutions to fix this error.
Bottom Line
After reading this post, you should know how to fix the 0x80042109 error now.
If you are still struggling with this error, try the methods mentioned above.