For a game lover, this issue is too annoying.
RSOD is a rare critical problem.
It always happens when demanding processing tasks like playing high-end video games.

power cycle your gear: Some temporary files could be the cause red screen while playing games.
But you could simply kickstart your PC to delete all temporary files.
We collect some other useful solutions here.

Solve Steam and Game Related Issues
Fix 1.
Update Steam
When you launch Steam, it will perform an automatic update.
But if you dont use Steam for a long time, it may miss some important updates.

This could be the reason for red screen of death while gaming.
So, just re-launch Steam and see if there is an available update.
Fix 2.

Update the Games
The game owner also keeps updating the game for a better experience.
If you launch the game using the shortcut, you could then launch the game from Steam instead.
Fix 4.

This could cause compatibility issue, resulting in read screen during gaming.
You candisable Steam Overlayto solve this problem.
Fix 5.
Switch to WINDOWED Mode
Running in full screen my cause compatibility issue like red screen of death while gaming.
you’re free to switch to the Windowed mode alternatively.
On the next page, expand the options next toDISPLAY MODE, and then selectWINDOWED.
Click theAPPLYbutton on the bottom to execute the change.
Solve Other Issues
Fix 1. you’re able to use these steps to switch to a compatibility mode:
Step 1.
Right-poke the game shortcut and select Properties.
ClickApplyand thenOKto save the change.
Play the game again and see if the red screen goes away.
Fix 2.
Change the In-game Graphics prefs to a Lower Option
The default game graphics prefs may not fit your situation.
you’re free to change the parameters to a lower mode.
you might use these steps to do this job:
Step 1.
Launch the game and go toOPTIONS.
SelectGRAPHICS OPTIONSfrom the left menu.
Adjust the following graphics elements:
Step 4.
Click theApplybutton to save the changes.
Now, you might launch the game and see if you might play the game without a red screen.
Fix 3.
To avoid this issue, you should disable them.
you could useMiniTool Power Data Recoveryto do this job.