It could be a frustrating experience.
Unfortunately, plenty of game players are experiencing the Cities Skylines 2 save disappeared issue.
If you are one of them, here are several methods for you to recover those lost game files.
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Way 1.
This happens because players start the game using the Resume feature instead of the Load feature.
Then, you’re able to continue with the proper game progress.

Want to access your saves of Cities Skylines 2?
This post guides you on how to find Cities Skylines 2 save file location for backup.
Way 2.
Open Steam Library to locate Cities Skylines 2.
Right-hit it and chooseProperty.
Change to theInstalled Filestab and clickVerify game file integrityon the right pane.
Way 3.
This free file recovery software is developed to restore types of files that are saved on Windows.
MiniTool Power Data Recovery FreeClick to Download100%Clean & Safe
Step 1.
Launch the software and chooseSelect Folderat the bottom section.
you could navigate to the save file location of Cities Skylines 2:C:\Users\username\AppData\LocalLow\Colossal Order\Cities Skylines II\Saves.
Tick the files and clickSaveto choose a recovery destination.
Remember that prevention is always better than cure.
Hope this post helps you indeed.